“Why a LINC”?

LINC: A Compact Yet Powerful Coordination Environment

This paper presents LINC, a coordination programming environment. It is an evolution of earlier middlewares (the Coordination Language Facility (CLF) and Stitch). The aim is to provide a more flexible and expressive language correcting several of their limitations and an improved run-time environment. LINC provides a compact yet powerful coordination language and an optimised run-time which exe...

Build a braveheart: the missing linc (RNA).

Why Believe That There Is a God?

This article presents an argument for the existence of God, showing that the evident phenomena are best explained by supposing that a God causes them. The argument is based on the inductive force of four very evident general phenomena: that there is a physical Universe; that it is governed by very simple natural laws; that those laws are such as to lead to the existence of human bodies; and tha...

Structural insights into LINC complexes.

Communication between nucleus and cytoplasm extends past molecular exchange and critically includes mechanical wiring. Cytoskeleton and nucleoskeleton are connected via molecular tethers that span the nuclear envelope. Sad1, UNC84 (SUN)-domain proteins spanning the inner nuclear membrane and Klarsicht, ANC-1 and SYNE/Nesprin-1 and -2 Homology (KASH)-peptide bearing proteins residing in the oute...

LINC: biology's revolutionary little computer.

The 1963 LINC (Laboratory INstrument Computer) stands at the center of two stories: the computerization of the biologist's laboratory and the advent of small-scale computing. The brainchild of Wesley Clark, 'the most brilliant computer designer of his generation', LINC was developed specifically to address the failure of biologists to adopt computer technology. To meet their unique needs, Clark...